Research Organization: Broad Institue
Contact Person: Not applicable
Contact Phone: Not applicable
Email Address: info@broad.mit.edu
Project Web Site: http://www.broad.mit.edu/mammals/dog/
Mast cell tumors (MCT) are cancerous proliferations of mast cells. Although they can and will spread throughout the body, the danger from mast cell tumors arises from the secondary damage caused by the release of chemicals that they produce. These chemicals can cause systemic problems that include gastric ulcers, internal bleeding, and a range of allergic manifestations. Clearly, mast cell tumors affect both lifespan and quality of life.
Osteosarcoma is the most common type of malignant bone cancer, accounting for 35% of primary bone malignancies. There is a preference for the metaphyseal region of tubular long bones. It is a malignant connective (soft) tissue tumor whose neoplastic cells present osteoblastic differentiation and form tumoral bone.
This study attempts to map risk factors for mast cell tumors or osteosarcoma respectively.
If you suspect that your dog has a mast cell tumor or osteosarcoma, please contact the Broad Institute at the email address above and ask how to proceed to submit a blood sample to participate.
Data Sheet Name: Broad.html Last Updated: Sep 6 2007 Proofed: AJH, PL